# Alebund Pharmaceuticals (09637.HK) Debuts on the HKEx Main Board

- Link: https://www.thailand-business-news.com/pr-news/alebund-pharmaceuticals-09637-hk-debuts-on-the-hkex-main-board
- Published: 2026-06-29T19:00:00+07:00
- Author: PR Newswire

_Deepening Its Commitment to Kidney Disease and Accelerating Toward Becoming a Global
Leader in Renal Innovation_

SHANGHAI, June 29, 2026 /PRNewswire/ — Alebund Pharmaceuticals (Jiangsu) Limited("
Alebund" or the "Company"; stock code: 09637.HK), a biopharmaceutical company focused
on kidney disease, with the broadest pipeline by renal indication coverage, today
listed on the Main Board of The Stock Exchange of Hong Kong Limited (the "Stock 
Exchange"). The Global Offering marks Alebund’s entry into the international capital
markets, positioning the Company as a scarce, innovation-driven renal-focused asset
in Hong Kong’s capital market.

The Global Offering comprised a total of 56,755,400 H Shares at an Offer Price of
HK$22.60 per Offer Share, consisting of 5,675,600 H Shares under the Hong Kong Public
Offering and 51,079,800 H Shares under the International Offering. Without taking
into account any exercise of the Over-allotment Option (the "Greenshoe"), total 
gross proceeds amounted to approximately HK$1.283 billion (approximately US$164 
million). If the Over-allotment Option (up to 8,513,300 H Shares) is exercised in
full, the total gross proceeds will increase to approximately HK$1.475 billion (
approximately US$189 million). After deducting offering expenses, the Company estimates
that the net proceeds from the Global Offering will be approximately HK$1.181 billion.

Following the market open today, Alebund’s shares show strong performance; as of
the close, the share price rose 103.54%, closing at HK$46.0 per share.

[⌊Alebund Pharmaceuticals lists on the Main Board of The Stock Exchange of Hong 
Kong Limited⌉⌊Alebund Pharmaceuticals lists on the Main Board of The Stock Exchange
of Hong Kong Limited⌉[
Alebund Pharmaceuticals lists on the Main Board of The Stock
Exchange of Hong Kong Limited

The Global Offering attracted a strong line-up of cornerstone investors, including
GIC, Loomis Sayles, RTW, SymBiosis, Tencent, Cormorant, Dymon Asia, GF Fund, China
Universal, E Fund and Loyal Valley Capital, among other renowned institutions. The
cornerstone investors subscribed for a total of approximately US$81.5 million (approximately
HK$639 million), representing approximately 49.78% of the shares offered under the
Global Offering. The International Offering was approximately 19.77 times oversubscribed,
and the Hong Kong Public Offering was approximately 963.56 times oversubscribed,
reflecting enthusiastic demand. The strong cornerstone line-up and robust market
response fully demonstrate the global capital markets’ high recognition of the scarcity
value of Alebund’s innovative renal pipeline, as well as their firm confidence in
the Company’s core value and long-term development potential.

**A Broad and Well-Balanced Renal Innovation Pipeline

Alebund has built the industry’s broadest pipeline in terms of kidney disease indication
coverage:

 ◦ AP301 is a best-in-class oral phosphate binder for hyperphosphatemia in chronic
   kidney disease (CKD) patients on dialysis, with its registrational Phase III 
   trial in China having met the primary endpoint, a New Drug Application (NDA) 
   to the National Medical Products Administration (NMPA) planned for the near future,
   and its China-U.S. Phase III multi-regional clinical trial (MRCT) having completed
   enrollment.
 ◦ AP306 is a first-in-class pan-phosphate transporter inhibitor that has received
   Breakthrough Therapy Designation (BTD) from the NMPA and whose rights outside
   Chinese Mainland, Hong Kong, Macau and Taiwan have been licensed to R1 Therapeutics.
   China Phase II data demonstrated monotherapy reducing mean serum phosphate by
   2.51 mg/dL from baseline and approximately 95% of patients achieving serum phosphate
   below 5.5 mg/dL by Week 7-8 (versus approximately 50% for the active control,
   sevelamer carbonate, in the same trial).
 ◦ AP303 is a first-in-class, differentiated dual PPAR agonist designed to delay
   or halt the progression of CKD across potential indications including diabetic
   kidney disease (DKD) and IgA nephropathy (IgAN), and has received Orphan Drug
   Designation (ODD) for Autosomal Dominant Polycystic Kidney Disease (ADPKD) from
   the U.S. FDA. In the completed Phase I trials in Australia and China, AP303 demonstrated
   favorable safety and was well tolerated in healthy volunteers as well as in patients
   with DKD, and there was a clear and robust dose-dependent pharmacodynamic ("PD")
   signal. Alebund has received IND clearance from the NMPA and the FDA for AP303,
   and expects to conduct a basket Phase II clinical trial in DKD and IgAN patients
   in the second half of 2026.
 ◦ AP308 is a first-in-class engineered recombinant IgA protease aiming for a functional
   cure of IgAN. The Company plans to submit an IND to the U.S. FDA and China’s 
   NMPA in the third quarter of 2026 and to enter the clinical development stage.
 ◦ The Company’s commercialized renal anemia product Mircera®, a long-acting ESA(
   erythropoiesis-stimulating agent), continues to gain traction, marking Alebund’s
   accelerating transition from biotech to biopharma.

**Focusing on the "Silent Majority" and Addressing Vast Unmet Needs**

Kidney disease is a long-underestimated field with vast unmet clinical needs. There
are more than 800 million people living with chronic kidney disease worldwide, including
nearly 124 million patients in China. Taking hyperphosphatemia as an example, approximately
76% of dialysis patients in China have uncontrolled serum phosphate levels — far
higher than in the United States (52%) and Japan (39%) — reflecting a treatment 
need that is real, long-term and structural. Alebund firmly focuses on kidney disease,
the "silent majority," committed to providing higher-quality and more accessible
treatment options for kidney disease patients worldwide.

**Messages from Management**

Dr. Gavin Xia, Co-founder, Chief Executive Officer and Chairman of the Board of 
Alebund, said: "Listing on the Main Board of The Stock Exchange of Hong Kong Limited
is an important milestone in Alebund’s journey. Alebund’s rapid growth and successful
listing on the Hong Kong Stock Exchange would not have been possible without the
relentless efforts of our team, nor without the support of government authorities
at all levels, our investors, and partners across all sectors. From this new starting
point, Alebund will continue to accelerate the clinical and commercialization progress
of its product pipeline, further upgrade its globally competitive integrated kidney
disease platform, reward shareholders and partners with even stronger performance,
and safeguard patients worldwide with higher-quality kidney disease treatment solutions."

Dr. Jin Tian, Co-founder and Chief Medical Officer of Alebund, said: "Alebund is
dedicated to overcoming the persistent therapeutic challenges associated with chronic
kidney disease and has established a highly differentiated and innovative product
pipeline. Our lead asset, AP301, has successfully completed a Phase III registrational
trial in China and is on track for New Drug Application (NDA) submission, which 
we expect to provide a better option for the management of hyperphosphatemia in 
patients receiving dialysis. In parallel, we are rapidly advancing the clinical 
development of our follow-up pipeline candidates, striving to bring next-generation
therapies to patients with renal disease as quickly as possible."

**About Alebund Pharmaceuticals**

Alebund Pharmaceuticals (09637.HK) was established in Shanghai, China in early 2018.
It is a biopharmaceutical company focused on kidney disease and related chronic 
diseases, with the broadest pipeline in terms of renal indication coverage, principally
engaged in the discovery, development, manufacturing and commercialization of innovative
drugs in these areas, with the aim of providing better clinical treatment solutions
for patients with chronic kidney disease and related diseases worldwide. Alebund
has established a rich and well-balanced pipeline of innovative kidney disease drugs,
including seven product candidates and one commercialized product (Mircera®), with
indications spanning hyperphosphatemia, renal anemia, IgA nephropathy (IgAN), diabetic
kidney disease (DKD), focal segmental glomerulosclerosis (FSGS) and autosomal dominant
polycystic kidney disease (ADPKD), among others. The Company has built and commenced
operations at a manufacturing facility in Yangzhou, Jiangsu, which has obtained 
a Drug Manufacturing License (Category B) issued by the Jiangsu Provincial Drug 
Administration, to support the future commercialization of AP301 and other pipeline
products. The Company has also established a specialized nephrology sales team responsible
for the commercialization of related products in China.

Company website: [www.alebund.com](https://www.alebund.com/)

**Forward-Looking Statements**

This press release contains certain forward-looking statements relating to the Company’s
future plans, clinical development and registration progress, commercialization 
prospects and industry trends, among other matters. These statements are based on
the Company’s judgments and assumptions as of the date of this press release and
are subject to various risks and uncertainties; actual results may differ materially
from such forward-looking statements. This press release does not constitute an 
offer to sell or a solicitation of an offer to purchase any securities. For complete
information on the Global Offering, please refer to the prospectus published by 
the Company.

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