# Everest Medicines Enters Commercialization License Agreement with Mabworks for Bejescin® in the Asia-Pacific Market

- Link: https://www.thailand-business-news.com/pr-news/everest-medicines-enters-commercialization-license-agreement-with-mabworks-for-bejescin-in-the-asia-pacific-market
- Published: 2026-06-04T17:32:00+07:00
- Author: PR Newswire

◦ Everest Medicines has obtained exclusive rights for the clinical development 
   and commercialization of Bejescin^(®) (MIL62, Obinutuzumab beta Injection) across
   the Asia-Pacific region, including Southeast Asia, India, South Korea, Australia,
   New Zealand, Hong Kong SAR, Macao SAR, and Taiwan region, China.
 ◦ Under the terms of the agreement, Everest Medicines will pay Mabworks an upfront
   payment of RMB 23 million and sales milestone payments of up to RMB 186 million.
   Mabworks will also be eligible to receive a share of gross profit in the region.
 ◦ This collaboration will strengthen Everest Medicines’ presence in nephrology 
   and autoimmune diseases across the Asia-Pacific region, creating synergies with
   its nephrology portfolio.

SHANGHAI, June 4, 2026 /PRNewswire/ — Everest Medicines (HKEX 1952.HK, "Everest",
or the "Company"), a biopharmaceutical company focused on the discovery, clinical
development, manufacturing and commercialization of innovative therapeutics, today
announced that it has entered into a commercialization license agreement with Beijing
Mabworks Biotech Co., Ltd. ("Mabworks"), under which the Company has obtained exclusive
rights for the clinical development and commercialization of Bejescin^(®) (MIL62,
Obinutuzumab beta Injection) across the Asia-Pacific region, including Southeast
Asia, India, South Korea, Australia, New Zealand, Hong Kong SAR, Macao SAR, and 
Taiwan region, China.

This collaboration will strengthen Everest Medicines’ presence in nephrology and
autoimmune diseases across the Asia-Pacific region, creating synergies with its 
nephrology portfolio. Leveraging its established and proven clinical development
and commercialization capabilities, the company aims to advance the development 
of Bejescin^(®) and support its launch in the Asia-Pacific region, while furthering
its long-term strategy in the global innovative medicines market.

Under the terms of the agreement, Everest Medicines will pay Mabworks an upfront
payment of RMB 23 million and sales milestone payments of up to RMB 186 million.
Mabworks will also be eligible to receive a share of gross profit in the region.

Bejescin^(®) (MIL62, Obinutuzumab beta Injection) is a novel third-generation anti-
CD20 monoclonal antibody. It was approved in China in February 2026 for the treatment
of neuromyelitis optica spectrum disorder (NMOSD), becoming the first CD20 antibody
approved for this indication globally and the first domestically developed therapy
in China. The New Drug Application (NDA) for primary membranous nephropathy (PMN)
is currently under Priority Review by the National Medical Products Administration(
NMPA), with the potential to become the first approved targeted therapy for PMN 
worldwide. Bejescin^(®) is also in Phase III trials for systemic lupus erythematosus(
SLE) and follicular lymphoma (FL), with potential for further expansion into other
autoimmune indications.

"We are delighted to collaborate with Mabworks on Bejescin^(®). As the first CD20
antibody approved globally for NMOSD, Bejescin^(®) has demonstrated strong clinical
potential and significant opportunities in nephrology and autoimmune diseases," 
said **Mr. Yifang Wu, Chairman of the Board of Everest Medicines**. "This collaboration
strengthens Everest’s portfolio in these therapeutic areas and complements our existing
pipeline. With our expertise in clinical development and commercialization, we are
confident in advancing Bejescin^(®) across the Asia-Pacific region, bringing this
innovative therapy to more patients and improving access. At the same time, we are
committed to further strengthening Everest Medicines’ presence in the Asia-Pacific
and global innovative medicines market."

"We are thrilled to announce our partnership with Everest Medicines on Bejescin^(
®) across the Asia-Pacific region. As the first approved CD20-targeted therapy for
NMOSD worldwide and the potential global first targeted therapy for PMN, Bejescin
^(®) possesses exceptional product competitiveness and market potential." said **
Mr. Luning Chen, President of Mabworks.** "Since its launch in Mainland China, Bejescin
^(®) has achieved outstanding commercial performance. This collaboration will further
strengthen Bejescin^(®)‘s commercial network and brand influence across the Asia-
Pacific region, bringing ‘New Hope’ to more patients with renal and autoimmune diseases."

Bejescin^(®) has shown meaningful clinical and therapeutic benefits across nephrology
and multiple autoimmune disease areas, with potential for further indication expansion.
Its development in NMOSD, PMN, and SLE is expected to provide more innovative treatment
options for patients.

NMOSD is a debilitating autoimmune disorder targeting the central nervous system
characterized by high recurrence and disability rates, predominantly affecting young
and middle-aged women. The disease typically presents acute or subacute onset and
can progress rapidly, with approximately 90% of patients relapsing within three 
years. Severe cases may result in blindness or paralysis. Bejescin^(®) has demonstrated
a significant reduction in relapse risk as a monotherapy, with strong efficacy data
underscoring both its clinical value and the convenience.

PMN is one of the most common pathological types of adult nephropathy, with approximately
30%-40% of patients progressing to end-stage renal disease (ESRD) within 5 to 15
years. Globally, there are no approved targeted therapies for PMN. Phase III clinical
data demonstrated that Bejescin^(®) monotherapy provides significant advantages 
across multiple efficacy endpoints including complete clinical remission, complete
immunological remission and overall clinical remission. Furthermore, Bejescin^(®)
showed a favorable safety and tolerability profile, together with a convenient dosing
regimen. Following initial treatment, patients require only one intravenous infusion
every six months, reducing treatment burden and supporting long-term treatment adherence.

SLE is a chronic, systemic autoimmune disease that primarily affects young women.
For this indication, Bejescin^(®) is in Phase III clinical trial and offers the 
potential for administration every 24 to 28 weeks, addressing the need for long-
acting therapies and providing an improved treatment option for patients with SLE.

**About Bejescin® (MIL62)**

Bejescin^(®) (MIL62, Obinutuzumab beta Injection) is a novel 3rd-generation anti-
CD20 monoclonal antibody with a unique competitive position in the market, and has
been approved by NMPA for marketing in China for the treatment of Neuromyelitis 
Optica Spectrum Disorders (NMOSD), becoming the world’s first CD20-targeted antibody
therapy approved for NMOSD and the first approved domestically-developed therapy
for this indication in China.

In October 2025, Bejescin® was granted Breakthrough Therapy Designation (BTD) by
NMPA, becoming the first domestically developed therapy for the kidney disease to
receive this designation in China. Bejescin^(®)‘s New Drug Application (NDA) for
this indication is currently under the NMPA’s Priority Review, positioning it to
potentially become the first approved targeted therapy for PMN worldwide.

**About Everest Medicines**
Everest Medicines is a biopharmaceutical company focused
on discovering, developing, manufacturing and commercializing innovative pharmaceutical
products that address critical unmet medical needs for patients in global markets.
The management team of Everest Medicines has deep expertise and an extensive track
record both in China and with leading global pharmaceutical companies.

The Company’s therapeutic areas of focus include CKM (cardiovascular, kidney, and
metabolic), autoimmune, ophthalmology and critical care. Everest Medicines has developed
a fully integrated commercialization platform that combines omnichannel commercial
capabilities with end-to-end product lifecycle management. Leveraging its proprietary
mRNA platform, the Company is advancing its existing pipeline, including mRNA in
vivo CAR-T and mRNA cancer vaccines, while selectively expanding into additional
high-value therapeutic areas with blockbuster potential, and accelerating its global
expansion. For more information, please visit the Company’s website: [**www.everestmedicines.com**](http://www.everestmedicines.com/).

**About Mabworks**

Beijing Mabworks Biotech Co., Ltd. is a biopharmaceutical company in China dedicated
to discovering and developing innovative and differentiated antibody therapies, 
committed to becoming a world-class biopharmaceutical innovator with core products
and sustained R&D capabilities. Our mission is to translate scientific breakthroughs
in immunology and biology into novel antibody therapies that target a wide range
of autoimmune diseases and oncology, addressing significant unmet medical needs 
and market potential in China and globally. We will leverage this opportunity to
continuously provide innovative and affordable treatment solutions for patients.

**Forward-Looking Statements**
This news release may make statements that constitute
forward-looking statements, including descriptions regarding the intent, belief 
or current expectations of the Company or its officers with respect to the business
operations and financial condition of the Company, which can be identified by terminology
such as "will," "expects," "anticipates," "future," "intends," "plans," "believes,""
estimates," "confident" and similar statements. Such forward-looking statements 
are not guarantees of future performance and involve risks and uncertainties, or
other factors, some of which are beyond the control of the Company and are unforeseeable.
Therefore, the actual results may differ from those in the forward-looking statements
as a result of various factors and assumptions, such as future changes and developments
in our business, competitive environment, political, economic, legal and social 
conditions. The Company or any of its affiliates, directors, officers, advisors 
or representatives has no obligation and does not undertake to revise forward-looking
statements to reflect new information, future events or circumstances after the 
date of this news release, except as required by law

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