# Insilico Medicine And SK Biopharmaceuticals Achieved AI-powered Drug Discovery Collaboration Worth Up to 2.5 Billion for Neuroimmune Disorders

- Link: https://www.thailand-business-news.com/pr-news/insilico-medicine-and-sk-biopharmaceuticals-achieved-ai-powered-drug-discovery-collaboration-worth-up-to-2-5-billion-for-neuroimmune-disorders
- Published: 2026-06-22T11:37:00+07:00
- Author: PR Newswire

CAMBRIDGE, Mass., June 22, 2026 /PRNewswire/ — Insilico Medicine ("Insilico", 3696.
HK), a clinical-stage generative artificial intelligence (AI)-driven drug discovery
company, and SK Biopharmaceuticals, a Korean-based company leads the way in biotech
innovation with groundbreaking drug research, development, and commercialization
worldwide, announced a research and development collaboration at the BIO 2026 International
Convention to discover AI-enabled innovative drug candidates in the neuroimmune 
area of the central nervous system (CNS).

Neuroimmune disorders, including neuroinflammatory, neurodegenerative, and rare 
neurological disorders, remain among the most challenging therapeutic areas in modern
medicine, with significant unmet patient need and historically low clinical success
rates.

Under the agreement, Insilico will leverage its proprietary Pharma.AI platform, 
which spans target validation, generative chemistry, and molecule optimization, 
together with its preclinical drug discovery expertise to discover, design, and 
optimize novel candidates for neuroimmune indications. SK Biopharmaceuticals will
contribute its extensive development and clinical capabilities in neuroimmune disorders,
steering the late-stage development and commercialization of all resulting programs.
Together, the two companies aim to accelerate discovery timelines and advance next-
generation therapies for patients worldwide.

Financially, Insilico will be eligible to receive up to $18 million in upfront and
near-term milestone payments. The total potential deal value exceeds $2.5 billion,
including development, regulatory, and commercial milestone payments, as well as
single-digit royalties on net sales upon commercialization. Notably, the partnership
sets a record by total potential deal value that Insilico has secured with APAC 
partners to date.

"This collaboration represents an important milestone in expanding our growth beyond
epilepsy into new CNS therapeutic areas, building on the deep CNS expertise we have
established through the successful development and commercialization of Cenobamate,"**
said Donghoon Lee, President and CEO of SK Biopharmaceuticals.** "By combining Insilico’s
AI-powered drug discovery platform with SK Biopharmaceuticals’ clinical development
and U.S. commercialization capabilities, we believe we can accelerate the discovery
of innovative CNS therapies for patients. Beyond a single program, we see this collaboration
as a scalable and repeatable growth platform that can be leveraged for future target
discovery and development opportunities."

"We are delighted to announce this great news at the 2026 BIO International Convention,
which underscores the tremendous power of industry communication and collaboration
in accelerating progress in healthcare,"** said Dr. Alex Zhavoronkov, founder, co-
CEO, and CBO of Insilico Medicine.** "SK Biopharmaceuticals is a visionary partner,
merging global leadership and commercialization expertise with a forward-thinking
embrace of AI. By uniting Insilico’s AI-driven target-to-candidate engine with SK
Biopharmaceuticals’ deep CNS mastery, we aim to unlock breakthrough therapies, spanning
both traditional small molecules and advanced new modalities, to address critical
patient needs."

As an AI-native biotechnology company, Insilico is redefining the efficiency of 
preclinical drug development through its advanced AI and automation platform, setting
a new standard for the industry. While traditional early-stage drug discovery typically
takes 2.5 to 4 years, Insilico has consistently reached preclinical candidate (PCC)
nomination in an average of just 12 to 18 months, with only 60 to 200 molecules 
synthesized and tested per program. Since 2021, the company has nominated 31 PCCs,
13 of which have received IND approval or clearance.

While expanding the practical applications of its technology in drug discovery and
life science research, Insilico is also continuously enhancing the performance of
its AI platform. Drawing on extensive experience and datasets from its training 
platform, the company has distilled thousands of benchmarks and integrated them 
into MMAI Gym. Serving as both a "trainer and benchmark" for scientific AI, MMAI
Gym enables organizations to train models for domain-specific reasoning while rigorously
evaluating their performance on real-world tasks, advancing the path toward pharma
superintelligence. To date, Human Longevity and Liquid AI have collaborated with
Insilico, joining as partners of  MMAI Gym.

**About Insilico Medicine**

Insilico Medicine is a pioneering global biotechnology company dedicated to integrating
artificial intelligence and automation technologies to accelerate drug discovery,
drive innovation in the life sciences, and extend healthy longevity to people on
the planet. The company was listed on the Main Board of the Hong Kong Stock Exchange
on December 30, 2025, under the stock code 03696.HK.

By integrating AI and automation technologies and deep in-house drug discovery capabilities,
Insilico is delivering innovative drug solutions for unmet needs including fibrosis,
oncology, immunology, pain, and obesity and metabolic disorders. Additionally, Insilico
extends the reach of Pharma.AI across diverse industries, such as advanced materials,
agriculture, nutritional products and veterinary medicine. For more information,
please visit [www.insilico.com](http://www.insilico.com/)

**About SK Biopharmaceuticals**

SK Biopharmaceuticals is a global biotech company focused on the research, development,
and commercialization of innovative therapies for central nervous system (CNS) disorders
and beyond. The company achieved a historic milestone as the first Korean pharmaceutical
company to independently develop and commercialize a novel drug in the United States
with XCOPRI® (cenobamate), an innovative treatment for epilepsy.

Through its U.S. subsidiary, SK Life Science, Inc., SK Biopharmaceuticals has established
a direct commercial platform in the United States while expanding its global footprint
through strategic partnerships across Europe, Latin America, the Middle East, North
Africa, and Asia. The company continues to broaden patient access and strengthen
its long-term growth potential through ongoing label and geographic expansion efforts.

Building on its commercial success, SK Biopharmaceuticals is advancing a diversified
pipeline and investing in next-generation growth drivers, including radiopharmaceutical
therapies (RPTs) and targeted protein degradation (TPD). Through open innovation
and collaborations with leading global institutions and companies, the company continues
to expand its innovation ecosystem and R&D capabilities.

SK Biopharmaceuticals is also leveraging AI and digital technologies across the 
drug discovery, development, and treatment continuum to enhance patient outcomes
and experiences. By integrating scientific innovation with digital healthcare solutions,
the company aims to build a patient-centered healthcare ecosystem and realize its
vision of becoming a balanced Big Biotech.

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