# Shanghai SinoUnited Hospital Announced Availability of World's First CAR-T Therapy for Solid Tumors in Advanced Gastric Cancer

- Link: https://www.thailand-business-news.com/pr-news/shanghai-sinounited-hospital-announced-availability-of-worlds-first-car-t-therapy-for-solid-tumors-in-advanced-gastric-cancer
- Published: 2026-07-03T12:36:00+07:00
- Author: PR Newswire

SHANGHAI, July 3, 2026 /PRNewswire/ — Shanghai SinoUnited Hospital today announced
the availability of satricabtagene autoleucel ("satri-cel"), the world’s first chimeric
antigen receptor (CAR) T-cell therapy approved for the treatment of solid tumors,
for eligible patients with Claudin18.2-positive, HER2-negative advanced gastric 
or gastroesophageal junction (GEJ) adenocarcinoma who have failed at least two prior
lines of therapy.

This milestone marks a historic breakthrough in oncology by extending CAR-T therapy
from hematologic malignancies to solid tumors for the first time, while also highlighting
Shanghai SinoUnited Hospital’s ability to rapidly introduce innovative oncology 
therapies and apply advanced immunotherapies in clinical practice.

Gastric cancer remains one of the most prevalent and deadly malignancies worldwide.
Despite progress in chemotherapy, targeted therapy, and immunotherapy, outcomes 
for patients with relapsed or refractory disease remain poor, underscoring a significant
unmet medical need.

The approval of satri-cel represents a major advancement in precision immunotherapy.
CAR-T therapy, which involves genetically engineering a patient’s own T cells to
recognize and eliminate tumor cells, has transformed the treatment landscape for
hematologic malignancies. However, its application in solid tumors such as gastric
cancer has historically been limited by the complexity of the tumor microenvironment
and immune evasion mechanisms. The successful development and approval of CT041 
mark a critical step forward in overcoming these challenges.

Clinical evidence from the pivotal CT041-ST-01 randomized controlled trial demonstrated
meaningful efficacy in heavily pretreated patients. In the modified intention-to-
treat population, satri-cel achieved an objective response rate of 41% compared 
with 4% in the control group, along with a disease control rate of 81% versus 27%.
The treatment significantly improved progression-free survival, reducing the risk
of disease progression or death by up to 70%. Overall survival analysis further 
demonstrated a 53 to 63% reduction in mortality risk after statistical adjustment,
highlighting its potential to deliver clinically meaningful benefit in a population
with extremely limited treatment options.

As one of China’s leading private medical institutions, Shanghai SinoUnited Hospital
is now among the select clinical centers providing access to satri-cel under approved
indications. The hospital has established a structured multidisciplinary oncology
framework to support advanced cellular therapies, including comprehensive patient
evaluation, molecular diagnostics, individualized treatment planning, infusion coordination,
and continuous post-treatment monitoring. Its clinical focus spans a broad range
of tumor types, including gastrointestinal, lung, breast, thyroid, gynecologic, 
urologic, and soft tissue sarcomas, with a strong emphasis on multidisciplinary 
decision-making and personalized treatment strategies.

The center is supported by a nationally and internationally recognized multidisciplinary
expert team across major oncology subspecialties. This includes leading colorectal
cancer specialists Prof. Minhui Zheng and Prof. Xinxiang Li; experts in gastric,
hepatobiliary, and pancreatic cancers Prof. Weize Wu, Prof. Jian Zhu, and Dr. Min
Xu; urologic oncology specialist Prof. Dingwei Ye; gynecologic oncology expert Prof.
Xiaohong Xue; breast cancer specialists Prof. Guangyu Liu, Prof. Cheng Wang, and
Prof. Hui Ren; lung cancer experts Prof. Quan Wang, Prof. Jay Zhang, and Prof. Jiang
Fan; thyroid cancer specialists Prof. Shawn Qu, Prof. Bin Jin, and Prof. Bo Wu; 
and medical oncologists Dr. Qi Li and Dr. Haiyan Yang. Together, this multidisciplinary
structure ensures that patients benefit from coordinated, evidence-based, and highly
individualized cancer care across all stages of treatment.

"The availability of satri-cel represents a transformative milestone in the treatment
of advanced gastric cancer and signals the beginning of a new era in solid tumor
immunotherapy, "said Dr. Kathy Shi, Founder and CEO of SinoUnited Health, "As CAR-
T therapy continues to expand beyond hematologic malignancies, our institution remains
committed to ensuring that patients have timely access to innovative therapies supported
by strong clinical evidence and delivered through an integrated, multidisciplinary
care model."

Shanghai SinoUnited Hospital has previously established clinical experience in the
application of CAR-T therapy in hematologic malignancies. Over the past year, the
hospital has treated more than 30 patients with hematologic cancers using CAR-T 
therapy and has provided consultation and evaluation services to over 100 patients
considered for CAR-T treatment. Through this experience, the hospital has developed
comprehensive expertise in CAR-T-related patient management, including toxicity 
monitoring, risk stratification, and multidisciplinary supportive care, enabling
the safe and effective delivery of cellular immunotherapies in complex clinical 
settings.

The introduction of satri-cel at Shanghai SinoUnited Hospital underscores the hospital’s
ongoing commitment to advancing precision oncology and cellular immunotherapy. By
integrating global innovation with clinical practice, the hospital aims to accelerate
the translation of scientific breakthroughs into accessible treatment options for
patients with advanced and previously refractory cancers.

As CAR-T therapy enters a new developmental era for solid tumors, Shanghai SinoUnited
Hospital will further enhance its clinical diagnosis and treatment capacity, boost
multidisciplinary collaboration, keep pace with the clinical application of novel
anti-cancer agents, and deepen exchange and cooperation with medical institutions
at home and abroad, so as to advance cancer care standards across China and worldwide.

**About SinoUnited Health**

Established in 2016 and anchored in Shanghai, SinoUnited Health(SUH) is a high-quality
private healthcare provider with the largest and most extensive medical network 
in the Yangtze River Delta Region. Upholding the concept of "Patient First," SUH
provides trustworthy, cost-controllable, and high-quality healthcare services that
meet both domestic and international standards.

Its international medical team strictly follows evidence-based guidelines and maintains
long-term collaboration with renowned medical institutions in China and abroad, 
ensuring patients receive reliable, world-class care. As a physician-driven institution,
SUH’s "General Practitioner+ Specialist" model offers holistic, professional, and
personalized solutions, making premium private healthcare accessible for every family.

For more information, please visit: [www.suhhealth.com](https://www.suhhealth.com)

Contact: SinoUnited Health, [internationalcare@suh.cn](https://www.thailand-business-news.com/pr-news/internationalcare@suh.cn)

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